The web tool presented here runs SimpleBox4Nano version 4.01 model published on 16/02/2024, based on the works below:

SimpleBox4Nano references:
• J. Meesters et al. A Model Sensitivity Analysis to Determine the Most Important Physicochemical Properties Driving Environmental Fate and Exposure of Engineered Nanoparticles. Environ. Sci.: Nano (2019), 6(7), 2049-2060. [link]
• J. Meesters et al. Multimedia Environmental Fate and Speciation of Engineered Nanoparticles: A Probabilistic Modeling Approach. Environ. Sci.: Nano (2016), 3(4), 715-727. [link]
• J. Meesters et al. SimpleBox4nano model definition: Multimedia Modeling of Engineered Nanoparticles with SimpleBox4nano: Model Definition and Evaluation. Environ. Sci. Technol. (2014), 48(10), 5726-5736. [link]
SimpleBox references:
• Hollander, A.; Schoorl, M.; van de Meent, D. SimpleBox 4.0: Improving the model while keeping it simple… Chemosphere (2016), 148, 99–107. [link]
• Schoorl, M.; Hollander, A.; van de Meent, D. SimpleBox 4.0. A multimedia mass balance model for evaluating the fate of chemical substances. RIVM Report (2015). [link]
• Den Hollander, H.; Van Eijkeren, J.; Van de Meent, D. SimpleBox 3.0: Multimedia mass balance model for evaluating the fate of chemicals in the environment. RIVM Report (2004), 601200003. [link]
• Brandes, L.; Den Hollander, H. SimpleBox 2.0: A nested multimedia fate model for evaluating the environmental fate of chemicals. RIVM Report (1996). [link]
• Meent, D. SimpleBox: A generic multimedia fate evaluation model. RIVM Report (1993). [link]
• Github repository: https://github.com/rivm-syso/SimpleBox/tree/xl4nano_version
• Zenodo repository: https://zenodo.org/records/10671831