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Intro | Decision trees | TGs - Guidelines | Project deliverables | Data and DBs | Regulatory information | RG framework overview | SSbD

Safe-and-Sustainable-by-Design (SSbD)

The European Commission (EC) has adopted a recommendation and its annexes for the promotion of research and innovation for safer and more sustainable chemicals and materials, which includes nanomaterials in the wider scope. Relevant information can be found at the announcement of the EC (here) while an overview of SSbD can be found here.

Related reports from JRC and other bodies:

A well-structured resource is provided by the EU H2020 project NanoCommons, in which users can find basic regulatory information and other materials of interest: https://nanocommons.github.io/user-handbook/SSbD/

The EU H2020 SABYDOMA and the HEurope IRISS network have organized workshops on SSbD, for which information can be found at the following links.

Tool name Description References Sector
ProSafe SbD Implementation Concept SbD implementation concept based on the NANoREG SbD concept. The four main elements are: #1 The workflows in industrial innovation processes or actor-specific needs #2 The Safety Dossier #3 The Safety Profile #4 Harmonized inventory of SbD protocols, procedures and data" TEMAS & IPC, 2016. SbD
Cenarios "CENARIOS, the first certifiable nanospecific risk management and monitoring system. CENARIOS provides a ""State-of-the Art"" hazard and risk assessment, encompassing risk monitoring tools to minimise the potential risks." Widler et al. 2016 Monitoring
NANoREG deliverable D6.04 Inventory of existing regulatory accepted toxicity tests applicable for safety screening of MNMs. The safety screening strategy identifies potential risks of MNMs at early stage of innovation. The basis for the screening strategy is formed by six key risk potentials for MNMs: solubility/dissolution rate, stability of coating, accumulation, genotoxicity, inflammation and ecotoxicity. The aim of this screening strategy is to bring information on potential health risks in line with the stage of innovation. Noorlander et al. 2016 SbD
Precautionary Matrix for Synthetic Nanomaterials (Swiss Precautionary Matrix) This tool helps to determine if exposure needs to be controlled, providing advice on whether a precautionary approach is required under normal working conditions, in the worst case scenario and for the environment. Höck et al. 2013 SbD
NANOREG SbD Concept NANoREG has developed a Safe-by-Design (SbD) concept for nanomaterials to achieve reduced uncertainty and risk management of innovative materials, products and processes at the time of market introduction; earlier, increased and improved interaction between innovators and regulatory authorities in trusted environments (so-called SAFE HOUSES) to share expertise and knowledge with innovators in order to identify uncertainties and potential risks, towards guidance for registration or market approval. The document presents definitions, state of the art for industrial processes, the SbD concept, toolbox and implementation. Sips et al. 2015 SbD
CTA Toolbox Constructive Technology Assessment describes a particular form of technology assessment where challenges and uses of new technologies and innovations are anticipated and the results of the analysis are fed back into the ongoing development, implementation and societal embedding of an innovation. The overall ambition is to broaden technology development and implementation by including a broad range of aspects and actors. http://www.cta-toolbox.nl SbD
Nanotechnology Consumer Product Inventory (CPI) The Nanotechnology Consumer Products Inventory (CPI) documents the marketing and distribution of nano-enabled products into the commercial marketplace. The CPI is a useful interactive database for educating consumers and legislators on the real-world applications of nanotechnology. Vance et al. 2015 // https://www.nanotechproject.tech/cpi/ Communication
Nano E-tox NanoE-Tox database is an online-available database that contains in-depth nanoecotoxicological information on eight ENMs accompanied by considerable amount of information on ENM physico-chemical properties, testing conditions and, to some extent, also on mechanisms of toxic action. Hence, NanoE-Tox enables the comparison of toxicity of ENMs across different test species and, in addition, could provide valuable input for computational toxicity modeling (e.g., QSARs) and risk assessment." Juganson et al. 2015 Communication
Ecoinvent database The ecoinvent database provides well documented process data for thousands of products, and aims to help making informed choices about their environmental impact. http://www.ecoinvent.org/ Monitoring